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9 Best Vitamin and Supplement Subscriptions – 2022 Readers’ Choice Awards

Marisa Haber
ByMarisa HaberOct 24, 2022 | 0 comments

Choosing the best multivitamins and supplements for your personal health goals and needs can be a challenge, especially when the names sound like science experiments and you aren't sure exactly how they benefit you. Some brands claim to include everything under the sun in their products, but oftentimes the ingredients they use are found in cheap, suboptimal forms which may not even supply your body with sufficient amounts of the nutrients it needs. Thankfully, there are several brands that rise above the competition and provide customers with high-quality nutrients and maintain full transparency about what's actually inside their products as well as explain what each ingredient does. We've compiled a list of brands readers and editors of MSA trust the most in the modern vitamin and supplement subscription world and hope that one or more of these brands will provide exactly what you're looking for in a health supplement.

Every year, we ask our readers to share their top recommended subscriptions of all types. Then we ask our experts to share what they know about each subscription to make it easy for you to know which subscription is right for you. Below, you’ll find our insights for shopping vitamin and supplement subscription boxes and see readers’ top choices for vitamins, supplements, powders, and other wellness products.

At the end of this list, we’ve provided some info about the factors we considered when building this list.

What To Look For When Shopping for Vitamin Subscriptions

Choosing the right vitamin subscription can be tricky - seeing results takes time and you might not be familiar with most of the ingredients, so it's important to do your research before committing. Consider your health goals and needs: are you looking for overall wellness, sleep aids, skincare, gut health, energy, etc. You want to make sure the subscription box you choose will be sending you products that you need in your everyday routine so you get your money's worth.

The Most Popular Vitamin Subscription Boxes

Read on for our reader’s recommendations for the best vitamin subscription boxes currently available. If we missed anything, drop us a comment. If you’ve tried one of these services, be sure to leave a quick review (even if you had a poor experience — your review can help other readers avoid subscription remorse).

1. Hum Nutrition

Best Vitamin Subscription For Affordable Supplements

group shot of colorful bottles of supplements laying on white background

What This Vitamin Subscription Delivers

Looking to start a healthier lifestyle? Not sure where to begin? Let Hum Nutrition help. The company offers high-quality supplements designed for your lifestyle. Hum Nutrition stands out to us and our readers for the extent of their personalization. This nutrition-based wellness subscription box offers curated supplement plans based on your personal dietary needs.

To get started, fill out a short personal quiz, and then a Hum Nutrition nutritionist will build a unique plan. You’ll still have the ability to edit your shipment — pick and choose the vitamins that focus on the areas most important to you, and you’re good to go. The pricing is affordable, and you’ll get discounts for larger orders.

Hum carries 36 different products to address a range of health, beauty, and mood concerns. We love their tongue-in-cheek supplement names like "Gut Instinct," "Hair Sweet Hair," and "Here Comes The Sun," --their packaging is also brightly colored and includes a brief description of its purpose on the bottles so you know exactly what you're reaching for. Most of Hum's supplements are vegan and non-GMO, those that aren't are marked clearly on the labels.


  • Online quiz creates a personalized vitamin plan.
  • Ability to customize plan allows you to add and subtract vitamins to your plan.
  • Dietitians are available via e-mail to answer any questions.


  • Supplements come in their respective bottles instead of daily vitamin packs.
  • You can save more with a 3-month plan but canceling before your third shipment means you'll be charged the difference.

What Readers Say:

“Their gummy supplements are delicious!” – Piper

Shipping: Orders of $50 or more ship free to the U.S. For orders under $50, a $5.95 shipping fee applies within the U.S. and $10.95 for international destinations.

Starting at $80.00
Shop Hum Nutrition
Not ready to buy? Add it to your Or, if you want to learn more, check out all our HUM Nutrition reviews.

2. Ritual

Best Vitamin Subscription For Basic Coverage And Age-Related Needs

Image via our review.

What This Vitamin Subscription Delivers

Ritual offers a monthly vitamin subscription that provides people with most of the essential nutrients they need in their optimal forms. Ritual offers several different versions of its Essential Multivitamin including one for women, men, teens, and children 4+. Both the women's and men's versions are available for 18+ and 50+, but there are also prenatal and postnatal formulations available for women as well.

All versions of Essential Multivitamin are vegan-friendly and come in delayed-release capsules, except for Children 4+ which is available in a plant-based gummy form. This product can be taken by mostly anyone, regardless of dietary preferences, however, it is highly appropriate for vegans and vegetarians to use this multivitamin as it contains several nutrients that are often found in lower quantities in a plant-based diet: vitamin B12, vitamin D3, vitamin K2, DHA, iron, zinc, and choline (this nutrient is only found in the prenatal, postnatal, and children's versions).

Each multivitamin contains between 9 and 15 nutrients and you can find each nutrient's sourcing and form here. Ritual is one of the most transparent vitamin brands around today and goes above and beyond to ensure that each customer knows the origin of each ingredient they include in its Essential Multivitamin as well as the type of manufacturing that was used to create it.


  • Uses the cleanest and most optimal forms of the nutrients included in their supplements.
  • The branding, packaging, and pills themselves are aesthetically beautiful.
  • They have a minty taste that makes them more enjoyable when swallowing.


  • They are on the pricier side at around $30 for 60 pills.
  • This is not a personalized multivitamin.

What Readers Say:

I love these. The minty flavor and pretty capsules make me want to take these every day. I'm so bad about vitamins, but I have no problem sticking to these. Ritual also gives you tips for remembering to take your vitamins, too. I have an extremely sensitive stomach, too, but these give me no trouble. I found after taking these consistently for 2 weeks I just felt better all around. -Elaine

Shipping: Ships for free to the U.S.

Starting at $33.00
Shop Ritual
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Ritual reviews.

3. Care/of

Best Range of Vitamins and Powders

What This Vitamin Subscription Delivers

Do you struggle to maintain a healthy supplement routine? Let Care/of take all the pain out of buying (and taking) vitamins and wellness products. This wellness subscription box ships personalized daily vitamin packs along with additional wellness items to your doorstep each month.

To get started, fill out the personalized quiz about your diet and lifestyle. Care/of will build you your own custom health plan, backed by actual science and vetted by nutritionists. All Care/of products are made from the most effective bio-available ingredients possible, designed to help you feel your very best. They’re also sustainably sourced.

Each box comes with 30 individual packs of vitamins. Your daily pack contains your curated mix of supplements — perfect to grab on the go. Keep forgetting to take your Care/of each day? Try using their app, where you can track how many days in a row you use your packs. You’ll achieve milestones with longer and longer streaks.

If you’ve got a good idea of your nutritional needs, you can build your own mix from their line of 30 vitamins, minerals, probiotics, powders, and more. Modify your custom vitamin packs at any time and try out new supplements whenever you’d like. Our readers love the versatility of this wellness subscription box; it’s an excellent way to upgrade your vitamins without spending a ton of time on research.


  • Wide variety of supplements to choose from including multivitamins, minerals, herbs, probiotics, collagen, and protein.
  • Monthly refills are shipped automatically.
  • Subscription plans are easy to modify based on your current needs.


  • Shipping fee for orders less than $20.
  • Products are not third-party certified.


“I love the variety and personalization.” – J

Shipping: Ships for free to the U.S. and Canada.

Starting at $20.00
Shop Care/of
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Care/of - Personalized Daily Vitamins reviews.

4. Rootine

Best DNA-Based Multivitamins

What This Vitamin Subscription Delivers

Rootine is a multivitamin subscription service offering users a completely custom formula based on an online lifestyle quiz, and an at-home DNA and blood test (users can also upload results from existing 23andMe or Ancestry.com accounts). Rootine's slow-release microbead delivery system ensures maximum absorption and accurate dose measurement–no capsules involved.

Start by taking the lifestyle quiz, which provides recommended nutrients and detailed explanations. Users can choose to proceed with the personalized nutrients, or they can go ahead with the DNA testing and blood testing, which personalizes the nutrient profile even further. Uniquely, users can continuously re-test and optimize their multivitamins for peak wellness.

Rootine costs $69/month for three months, and with this, users receive a precision formula which includes up to 19 clinically-proven nutrients.


  • Backed by science and DNA results
  • Unique microbead delivery system provides maximum results
  • A convenient, online process


  • Expensive at $69/month for three months, not including testing materials
  • There is no month-to-month subscription option

Shipping: Rootine ships within the U.S. only, including Alaska and Hawaii. Rootine does not ship to Puerto Rico, Guam, or the US Virgin Islands.

Starting at $69.00
Shop Rootine
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Rootine reviews.

5. Nurish by Nature Made

Best Variety of Supplements Based on Health Goals

What This Vitamin Subscription Delivers

Nurish by Nature Made is a subscription box that sends you personalized vitamin and supplements packs every month. This box is designed to meet your specific nutrient needs and delivers everything you need straight to your door. It's the perfect accountability buddy to start 2022 off right and prioritize wellness. Nurish has an in-depth list of supplements on their site that are organized by supplement type and health goal to make your search easier.

Take a 5-minute quiz to receive a personalized pack by Nurish or create your own custom packs by shopping the site yourself - they even have curated lifestyle packs like Everyday Glam, Everyday Active, and Everyday Relax if you want to hone in on a specific need. Once you've decided on your supplement plan, you can expect a 30-day regimen to arrive in the mail. Each box comes with daily pre-packaged pouches of your personalized daily vitamins. These pouches come with your name printed on them and a fun inspirational quote as well, just to make your daily intake a little more enjoyable.


  • The website is easy to navigate and organized based on the type of supplement and your areas of concern.
  • Prices are highly affordable.
  • Products are USP verified.


  • Doesn't check for supplement-drug interactions.
  • Doesn't connect you with a dietitian or healthcare professional if you have questions or concerns.

What Readers Say:

I started subscribing to nurish a couple of months ago and love how easy my vitamin and supplement routine has become. nurish makes it easy for me to stay on top of my health and start my mornings off right with my daily vitamin packs. I also loved the quiz aspect and how nurish is backed by science, connected to Nature Made which I've bought for years off the shelves! My quiz suggested a few vitamins/supplements I didn't even think of, to help what I was trying to achieve (more energy, brain health, muscle health, etc.). -Camille

Shipping: Ships for free to the U.S.

Starting at $30.00
Active Deal
25% off first order
Use Coupon Code NURISH4U
Shop Nurish by Nature Made
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Nurish by Nature Made reviews.

6. Persona

Best Custom Vitamin Pack Subscription

Persona Vitamin Review

What This Vitamin Subscription Delivers

Want to step up your vitamin and supplement game but don't want to spend a fortune on buying 20+ individual products? Persona offers one of the most personalized approaches to designing daily vitamin and supplement packs. Customers can create a fully customized vitamin subscription by completing an online assessment or they can choose from among several curated vitamin packs if they only want to use a few ingredients to focus on a single health area.

Customers who want to obtain their own personalized vitamins will first need to take Persona's online assessment. It's extremely thorough compared to most other vitamin quizzes and asks questions about medical history, medication use, health goals, and more. Once you've completed the assessment, Persona will apply its scientifically-backed algorithm in order to develop a personalized vitamin pack that's designed to meet your specific health needs.

Customers will receive both morning and evening vitamin packs that contain a different set of ingredients depending on their desired health outcomes.

Customers may also choose to select curated vitamin packs that are centered on more specific health goals, such as weight loss support, energy, or sleep. Since these vitamin packs typically contain half of the ingredients that come in Persona's personalized vitamin packs, they are usually cheaper, but the only catch is that you cannot add or remove ingredients from these packs.

While prices and ingredients vary, you can expect to pay around $60-100/month for a customized vitamin pack that contains around 6-10 ingredients whereas curated packs cost anywhere from $21.99 to $30.99 for 3-ingredient packs and up to $73.99 to $83.9 for 5-ingredient packs.


  • Asks in-depth questions in their quiz including medical history and medication use.
  • Considers supplement-drug interactions.
  • Offers curated vitamin packs for specific concerns that tend to be cheaper than the personalized packs.


  • Not currently third-party certified.
  • No Certificate of Analysis available for any of Persona's supplements.

Shipping: Ships to the U.S.

Starting at $21.00
Shop Persona
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Persona reviews.

7. Seed

Best Probiotic/Prebiotic Supplement Duo

best vitamins 2021 seed

Image via our review.

What This Vitamin Subscription Delivers

Seed is a brand with only one supplement on its menu: DS-01TM Daily Synbiotic. The goal of DS-01 is to aid your microbiome, located in your gut, and help replete its diversity and richness. This pill is both a prebiotic and probiotic designed to support gut health, gut barrier integrity, gut immune function, cardiovascular health, dermatological health, and micronutrient synthesis. The DS-01 contains probiotic strains that have been scientifically and clinically studied to provide a range of benefits for the body including digesting food, minimizing inflammation, and better-synthesizing nutrients. We love how this probiotic goes so much further than the OTC options, and because of its unique 2-in-1 casing, it doesn't need to be refrigerated and gets 100% of the probiotic ingredients to your colon.

Beyond the pill itself, Seed also scores points in the presentation. Consumers are sent an aesthetically pleasing frosted, green glass jar to house their monthly pills and a glass travel vial. We love stylish and reusable packing, plus the tray that houses these jars in the package is made from mushrooms and easily decomposes in the soil within 30 days and the refill packaging is made from corn foam which dissolves in water.


  • Transparency on bacterial strains used in probiotic and plenty of links to scientific studies on their effectiveness.
  • Sustainable and stylish packaging.
  • No refrigeration necessary.


  • Pricier than OTC probiotics.
  • Not recommended for anyone under 18.


I’ve taken Seed for a year now. I started taking it because I have rosacea. I wanted to see if it would improve my gut health. So last year my gut health was very very bad. I was Flush red after every meal...So I knew if I took something that it would take about a year to see any kind of results. So as of today, my gut health is better but it’s not the best. I’m able to eat more things than before but not everything. I don't think that it helps me with bloating or bowel movements...I was going to stop taking it to see if there is a difference next month. But overall, I FEEL good about the product. I really like that it’s a symbiotic and that I know specifically which probiotics I’m ingesting. - Jasmine

Shipping: Ships for free to the U.S. and Canada.

Starting at $49.99
Active Deal
15% off your first month of a new subscription
Use Coupon Code MYSUB15
Shop Seed
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Seed reviews.

8. mindbodygreen

Best Ultimate Multivitamin

return to balance bundle

What This Vitamin Subscription Delivers

mindbodygreen is a lifestyle media brand dedicated to inspiring you to live your best life – mentally, physically, spiritually, emotionally. Through a 360º approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, mindbodygreen has been a respected resource for over ten years for individuals looking deeper into the fundamentals of science-based holistic well-being.

mindbodygreen has expanded over the years into functional nutrition coaching, classes (varying from fitness to self-improvement), and then most recently, supplements. Their current supplements range from probiotics+, sleep support+, immune support, and cellular beauty (just to name a few).

We particularly love mindbodygreen's Ultimate Multivitamin+, a daily vitamin that includes 33 premium ingredients: 14 vitamins, 13 minerals, and six botanical bioactives.

mindbodygreen's site explains this multivitamin as:

a high-potency vegan formula delivers a complete array of essential vitamins, chelated and marine minerals, a built-in B complex leveraging methylation technology, algal vitamin D3, and longevity botanicals including glutathione, resveratrol, piperine, and a bouquet of carotenoids. In this next-generation multi for women and men, we optimized the dose, bioavailability, bioactivity, and gentleness of each ingredient.

The site is full of supplement options that are organized in a large drop-down menu that's easy to navigate. Once you choose a supplement, its page has an informative timeline at the bottom that illustrates how many weeks it will take to feel the effects of each ingredient in the supplement. There are also descriptions of each ingredient underneath the timeline, to help you better understand why they're included and how they benefit your body,


  • Best daily multivitamin, packed with beneficial ingredients for the body's daily functions.
  • 30-day money-back guarantee.
  • Cancel subscriptions at any time.


  • On the pricier side at $59 per month.
  • There is no personalized plan, so make sure to read through all of the supplements to make purchases that are right for you.

Shipping: Ships free to the United States, including Hawaii, Alaska, all US territories, and Canada.

Starting at $69.00
Active Deal
Save 15% off your first month! New subscriptions only; code cannot be combined with other offers.
Use Coupon Code MSA15
Shop mindbodygreen
Not ready to buy? Add it to your Or, if you want to learn more, check out all our mindbodygreen probiotic+ reviews.

9. Athletic Greens

Best All-In-One Vitamin Powder For Immune Support

Athletic Greens powder being mixed into cup of water by woman

What This Vitamin Subscription Delivers

Wouldn't it be great if you could sip down your vitamins and supplements in a single drink? Athletic Greens has crafted a mega-nutrient powder that contains 75 nutrients including vitamins, minerals, digestive enzymes, and much more. This formulation is centered upon immune system defense and contains an expansive list of antioxidants, adaptogens, and superfoods to assist the body in detoxication and liver support.

While this approach to vitamins and supplements is quite practical, some consumers will need to confirm whether or not they may have potential interactions between the use of certain medications and herbs contained in this vitamin powder. However, most people should be able to consume this product free of worries.

This product is best suited for individuals who want to use an all-in-one approach to taking their daily vitamins and supplements. Some customers may prefer to use individual products or other brands instead as this ingredient combination may lead to gastrointestinal discomfort in some individuals who have dietary sensitivities. Customers should also keep in mind that this product does not contain vitamin D3, omega fats, or iron so they will need to consume those nutrients through their diet or the use of supplements.


  • Each powder contains 100% of the daily value of many micronutrients.
  • Contains a wide range of antioxidants, adaptogens, and superfoods that support the body's daily functions.
  • Entirely plant-based, making it keto, paleo, and vegan-friendly.


  • Doesn't consider drug-supplement interactions.
  • Must remember to take it in the morning on an empty stomach for optimal absorption.

Shipping: Ships to the U.S., Canada, and Australia for $9; shipping to Europe varies in price.

Starting at $0.00
Shop Athletic Greens
Not ready to buy? Add it to your Or, if you want to learn more, check out all our Athletic Greens reviews.

How to Get The Most Out of Your Vitamin Subscription Once You’ve Picked

Once you’ve picked out the right box for you, make sure you get the most out of it. Most of these subscriptions personalize their supplements with the help of a quiz. These in-depth quizzes help determine the right supplements for you based on your daily activity, current health, and personal health goals. Skipping these quizzes could prevent you from learning about a specific vitamin or powder that you could greatly benefit from. Make sure you take these quizzes for a full evaluation. Once you get your regimen, read up on the suggested supplements - doing some extra research never hurts. Our final tip, stay consistent! Vitamins are a long-term commitment, results don't appear after just a week. Commit to at least three to four months of taking supplements to determine if your mélange of vitamins is taking effect.

Factors We Considered When Reviewing These Vitamin Subscriptions

This list features our fellow subscription fanatics’ top choices, and we can confidently recommend the subscriptions above since we’ve researched and reviewed them all. Factors we considered when reviewing these subscriptions include:

  • Price: Does the price of the vitamin subscription match the quality and quantity of the product?
  • Does It Work: We read the experiences of our reviewers, readers, medical professionals, and other outside sources to determine if these supplements actually do what they promise.
  • Ingredients: Are these the best ingredients on the market? How do they benefit your body?
  • Benefits Beyond the Vitamin: What other factors make this subscription worth it? Is the packaging attractive? Is it a sustainable brand? How effective are the personal quizzes? Do they have medical experts at the ready to answer your questions?
Marisa Haber
Marisa Haber
Marisa Haber is a freelance writer with a passion for all things fashion, beauty, lifestyle, and food! When she's not scrolling through Instagram to get the scoop on all the latest trends, she can be found walking around the city asking people if she can pet their dogs.

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